Below you will find pages that utilize the taxonomy term “dmso”
Blog
DREAM Breast Cancer Sub-challenges
I have been going over the sub-challenges before attempting to solve them. As I mentioned, there are three sub-challenges and somehow they are connected.
First, using given data and other possible data sources such as pathway databases, the causal signaling network of the phosphoproteins. There are 4 cell lines and 8 stimulus so they make total 32 networks at the end. Nodes are phosphoproteins and edges should be directed and causal (activator or inhibitor).
Blog
HPN-DREAM Breast Cancer Network Inference Challenge
Understanding signaling networks might bring more insights on cancer treatment because cells respond to their environment by activating these networks and phosphorylation reactions play important roles in these networks.
The goal of this challenge is to advance our ability and knowledge on signaling networks inference and protein phosphorylation dynamics prediction. Also, we are asked to develop a visualization method for the data.
The dataset provided is extensive and a result of RPPA (reverse-phase protein array) experiments.