DREAM Breast Cancer Sub-challenges

I have been going over the sub-challenges before attempting to solve them. As I mentioned, there are three sub-challenges and somehow they are connected. First, using given data and other possible data sources such as pathway databases, the causal signaling network of the phosphoproteins. There are 4 cell lines and 8 stimulus so they make total 32 networks at the end. Nodes are phosphoproteins and edges should be directed and causal (activator or inhibitor).